9/9 Pre-Exposure Prophylaxis study (treated before exposed to the virus)
et al., Research Square, doi:10.21203/rs.3.rs-72221/v1 (Preprint)
Association Between Inhaled Corticosteroid Use and the Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Nationwide Population-based Study in South Korea
Association Between Inhaled Corticosteroid Use and the Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Nationwide Population-based Study in South Korea
Retrospective 44,968 patients in South Korea, 7,019 on inhaled corticosteroids, showing no statistically significant differences in COVID-19 cases.
Lee et al., 9/9/2021, retrospective, South Korea, Asia, preprint, 5 authors.
risk of COVID-19 case, 32.6% lower, RR 0.67, p = 0.10, treatment 19 of 1674 (1.1%), control 95 of 5345 (1.8%), adjusted per study, odds ratio converted to relative risk, multivariate.
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.
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